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We take the time to understand our client’s needs, and use our expertise and experience to successfully develop pharmaceutical products for the global market.
Enhancing Therapeutic Potential of Poorly Soluble Drugs
Modern drug development is leading to an increasing number of drug molecules with poor aqueous solubility and bioavailability. Technologies that can improve drug bioavailability by enhancing solubility are becoming more commonplace.
Potential techniques for drug solubility enhancement include Solid Dispersion (Spray drying and Hot melt extrusion) and Lipid-based formulations (Solid lipid nanoparticles, niosomes, emulsion, Self micro-emulsifying drug delivery system). Many factors need to be considered during the design and optimization of these formulations. The appropriate technology can be selected considering the drug’s physical and chemical characteristics and the type of dosage form.